CoreTlage animation
CoreTlage™
Coral Based Articular Cartilage Regeneration
CoreTlage offers a new approach to cartilage repair and represents a step forward in orthopedic science. Powered by CoreBone's sustainable coral cultivation technology, it regenerates true hyaline-like cartilage - overcoming the limitations of current surgical techniques. With superior outcomes and scalable innovation, CoreTlage is poised to make a significant impact in the multi-billion-dollar orthopedic market while contributing to a new standard of care.
CoreTlage - Articular Cartilage Regeneration
CoreTlage, aims to regenerate damaged articular cartilage. Leveraging CoreBone specific corals that are raised for this purpose in our coral farm, CoreTlage demonstrated in pre clinical studies, an unmatched ability to regenerate hyaline based articular cartilage.
Clinical View
Implantation area after
4.5 months - full tissue
recovery (Circle)
Micro CT scan
CoreTlage implantation
sites at 4.5 months.
The graft is well integrated
into the transplant site
Histology
6 Months post implantation.
The defect is filled with new
bone and cartilage tissues.
Full regeneration observed
H&E, 1.25x
Cartilage formation process of CoreTlage
Sheep Study. 6 months follow up
CoreTlage 4.5 months
CoreTlage 6.0 months
The defects filled with new bone. Early
cartilage is growing over the new bone
tissue
Masson trichrome showing the
cartilage formation from
the woven bone
Masson trichrome showing the
closure of cartilage on
the bone surface
CoreTlage Status
CoreTlage is entering FIM (First In Man) stage, following the successful pre clinical phase which confirms the product safety and the ability to regenerate cartilage and bone alike.
Contact us to learn more about CoreTlage,
CoreBone and how you can contribute and
become part of this promising opportunity!
CoreTlage
White Paper
CoreTlage histopathology. Sheep model, at 6 months
Safranin O/fast Green; 100x orig. mag.
Zone A, 2nd Floor, Building 1, Phase III of Guangzhou International Bio Island Standard Industrial Unit
E-mail
info@core-bone.com