Coral Based Tissue Engineering
Safe Effective Remodels
Dental Bone Graft
CoreBone provides a safe, effective and proven alternative to bovine and human grafts - supported by global clinical success.
ABOUT COREBONE
CoreBone focuses on cultivating corals for tissue engineering in bone and cartilage, providing safe and effective solutions that shorten procedure and healing time. The global market for bone and cartilage repair is valued in the multi-billion-dollar range, reflecting both the scale of demand and the unmet clinical need.
Our proprietary coral cultivation technology (IP protected) provides a safe, consistent, and sustainable source of natural scaffolds-overcoming the limitations of bovine, human, and marine-harvested materials. CoreBone’s Dental solutions are supported by extensive research and successful clinical use worldwide. Since 2017, our coral bone grafts have been commercially available in selected markets, with thousands of procedures validating their safety and effectiveness.
Building on this foundation, we have developed and patented CoreTlage, a breakthrough cartilage regeneration platform. CoreTlage has demonstrated the ability to regenerate hyaline-like cartilage in preclinical studies and is now advancing into its first-in-man clinical phase.
CoreBone has strong ESG credentials, combining sustainable biotechnology, ethical medical innovation, and strong governance.
Why Cultivated Coral
Corals share similarities with bone in composition, structure, and biological properties, making them suitable for bone regeneration without the risks associated with animal or human bone.
Marine coral populations are endangered species and sensitive to marine pollution.
Our lab based coral growing technology ensures sustainable coral production under controlled conditions in a closed system, overcoming marine biological pollution and risks.
Core Technology - Cultivated Coral
Coral Farm
CoreBone cultivates corals in a closed, controlled aquarium system, utilizing proprietary technology and lab-formulated seawater rich in bioactive nutrients, along with CoreBone's exclusive coral propagation strains. This allows CoreBone to take full advantage of the coral's natural bone-like properties, avoid the risks associated with marine pollution, and ensure product consistency.
Why CoreBone
Early Osteoprogenitor Cell Integration
Layers of strained active osteoprogenitor cells attached to bioactive coral mineral surface (48 hours after grafting in vivo)
Strength
5 times stronger than human cancellous bone and synthetic grafts (compressive strength, MPa)
3D Porous Structure
Young woven bone deposited on the surface of grafted coral mineral; observed ingrowth of capillaries into the CoreBone graft
Bone & Cartilage Regeneration
Full bone & cartilage regeneration after 6 months in pre-clinical animal model
Experienced Team
Business, Science, Coral Growing
Prof. Haim Tal
DMD, PhD Scientific
Advisor - Dental
Ohad Schwartz
CEO, Co-founder
Assaf Shaham
Coral Farm Manager
Prof. Eyal Amar
Scientific Advisor - Sport Medicine and Knee
Senior orthopedic surgeon Sport medicine, arthroscopic knee surgery and sport medicine, Sorasky Medical Center, Tel Aviv
CoreBone Head Surgeon
Formed Head of the Department of Periodontology and Oral Implants and former dean of the Tel Aviv University School of Dental Medicine
MD from the University of Göttingen, DE Experienced in clinical practice
Responsible for the design and supervision of clinical trials for CoreBone
Noted coral grower, established coral farm early 2008
Lectures on aquaculture, Ben Gurion University, Eilat campus
Founder & CEO of CoreBone, leading the company from its initial idea through development and growth
Responsible for strategy, innovation, and market positioning since day one
Previously served as VP and Marketing Manager for international companies in the medical and consumer goods sectors
Dr. Xuan Zheng
MD, PhD Clinical Manager
Zone A, 2nd Floor, Building 1, Phase III of Guangzhou International Bio Island Standard Industrial Unit
E-mail
info@core-bone.com